Endocrine Abstracts

Introduction: 5-10% of papillary thyroid carcinoma develop metastatic disease, of which about 60-70% will become refractory to radioactive iodine. Significant negative impact on the prognosis and an average life expectancy of 3 to 5 years.Material and method: Since 2018, patients with refractory thyroid carcinoma and considered to be progressive according to the RECIST criteria have been treated with anti tyrosine Kinase type sorafenib.<p class="abst...

Introduction: Disorders of sex development include a large number of congenital conditions related to unusual chromosomal sex (gonosomal abnormalities), defective testicular development, or abnormal hormone secretion or receptivity, resulting in unusual external and/or internal genitalia development rare. Patients and methods we report 3 cases of disorders of sex development 46XY reveled at adult age. clinical, biological and radiological funding are reported in the following ...

Introduction: The Marine-Lenhart syndrome (MLS) is commonly defined as a combination of Graves’ disease and autonomous functioning thyroid nodule (s). the risk of malignancy of these nodules is less than 1% We report a case.Observation: 27-year-old patient, hospitalized for treatment of a basal disease, cervical ultrasound found a 1.5 cm lower left lobe thyroid nodule classified eutirads 4. the sintigraphy found an aspect of diffuse hypercaptive goi...

Introduction: Anaplastic thyroid cancer has long been considered as a mesenchymal tumor (sarcoma). To date, it is difficult to differentiate between the two types. Radio-induced sarcomas of the head and neck are a very rare entity. Their annual incidence is 0.06 to 0.17%.Observation: We report the case of a 83-year-old patient, with a history of breast neoplasia treated with radiotherapy 7 years ago. Followed for a year for papillary carcinoma of the thy...

Thyroglossal ductal cyst is the most common congenital cervical pathology. Abnormalities in the embryologic development and migration of the thyroid gland can result in this ectopic thyroid tissue, which may occur in the midline in any position from the base of the tongue to the mediastinum. They are rarely seen in adults. Malignant transformation of the cyst is quite rare and is encountered mostly in adults.We retrospectively reviewed two cases of thyro...

Polycystic ovary syndrome (PCOS) is the most frequent endocrinopathy in premenopausal women, and has many clinical features in common with the metabolic syndrome.Objective: The aim of our study was to evaluate the clinical characteristics of our PCOS women.Methods: Of 181 PCOS defined by the Rotterdam criteria and 90 controls were evaluated for anthropometric parameters by physical examination.Results: The PC...

Introduction: Adrenal cavernous hemangioma is a rare tumor with few cases reported in the world. Usually this adrenal masses are incidentally discovered and non functional.Case report: We describe the case of a 63 year old male patient with a history of hypertension and treated prostate. He was referred to our endocrinology department with complaints of his left lower back. At the admission the BMI was 21 kg/m2, his blood pressure was 160/90 m...

Introduction: Adrenal myelolipoma is a rare, benign and nonfunctional tumor composed of mature adipose and hematopoietic cells. It is often of incidental finding (8%) and the diagnosis is based on radiological imaging. We report two cases of giant adrenal myelolipoma and discuss the diagnostic and therapeutic aspects of this pathology.Observation: Patient D.K 40 years old, hospitalized for adrenal mass revealed by right back pain radiating to the right h...

Background: Von Hippel–Lindau (VHL) is a rare, autosomal dominant syndrome characterized by the development of highly vascularized tumors in multiple organs. VHL affects approximately 1 in 35,000 live births. Tumors associated with VHL include hemangioblastom of the retina and central nervous system, pheochromocytomas, endolymphatic sac tumors of the middle ear, and epididymal or round ligament cysts. In 80% of patients, VHL disease is familial caused by mutations in the ...

Introduction: Proximal myopathy presents as symmetrical weakness of proximal upper and/or lower limbs. There is a broad range of underlying causes including drugs, alcohol, endocrine and metabolic myopathies such as primary hyperparathyroidism.Observation: We describe a 48-year-old male, hospitalised in neurology departement for exploration of severe proximal myopathy. Cliniquely, he presented progressive debilitating muscle weakness, severe muscle wasti...